Human papillomavirus infection and possibilities of improving the effectiveness of therapy for recurrent anogenital warts.

Introduction. In recent years, there has been an increase in the number of cases anogenital warts, with localization urethra, which present significant difficulties management tactics due to high frequency relapses, progression clinical manifestations and damage underlying tissues. According a systematic review including PubMed EMBASE data, severe warts may be associated decrease local systemic immunity, level vitamin 25(OH)D zinc blood serum. The search for methods effectiveness therapy is very urgent problem. aim study was develop method increasing combined recurrent warts. Materials methods. included 25 men aged 24 50 diagnosis All patients had laboratory research human papillomavirus (HPV) scrapings; sexually transmitted infections; determination 25(OH)D, zinc. complex treatment extract Solanum tuberosum (Panavir) form: Panavir solution, Panavir-gel, Panavir-Intim spray topical use imichimod surgical destruction genital Results. Monitoring 6 months showed remission 23 men, reccurent distal section urethra – 2 patients. Conclusions. obtained efficiency inclusion treatment.